Screen for selecting solvents, polymorphs, salts or co-crystals has never been so easy after the introduction of the Crystal16 in 2005. The Crystal16 is a parallel crystallization platform that allows for fast screening of crystallization parameters in 16 parallel reactors with a volume of 1.5ml. The Crystal16 can be used for application of heating and cooling, for instance during polymorph or salt screening, but also for the determination of solubility as a function of temperature in e.g. process development and optimization. After more than 10 years of success in more than 300 companies, it is by far, the world’s most used equipment for solubility curves measurement and phase diagrams. New features in the Crystal16 include: eliminate the need for a chilled water supply, improved temperature range going from-15°C up to 150°C, overhead stirring and a new flexible software based on our successful software for the Crystalline.