CS Bio

CS136X / CS136M

IDEAL FOR R&D, PROCESS DEVELOPMENT OR SMALL-SCALE MANUFACTURING

• 20 – 200mL Reaction Vessel Size
• CS136 has a range of 0.1 to 4mmol.
• Translating to about 100mg to 7g of starting resin.
• Twenty-Two 100mL Amino Acid Reservoirs
• One 5L, four 2L, two 1L and two 250ml solvent reservoirs
• 180° Inversion mixing with nitrogen bubbling for complete solvent and resin contact
• Unlimited couplings, fully automated synthesis of sequences 130-mer or more with no user interaction
• Additional functional reaction vessels (up to 3)
• Heated synthesis with jacketed reaction vessels up to 90°C
• Additional solvent / amino acid reservoirs
• UV monitoring

CS536X / CS936S (PILOT SCALE)

• Our pilot scale instruments enable the user to make high purity peptide at the gram scale.
• The 536X with reaction vessels from 200mL to 2000mL
• The 936S with reaction vessels from 2 to 5L
• Typically to be used for toxicological studies, PK studies, formulation work, additional assay testing or simply just to synthesize larger batches.
• Fully validated software for process development or cGMP production
• Suitable for tBoc Fmoc or any other peptide chemistry
• Flow-through capabilities
• 22 amino acid reservoirs to utilize stock amino acid solutions
• Overhead stirring
• Allowing users to run a synthesis at multiple scales within the same and increase the batch size as their needs and research progress.
• 21 CFR Part 11 Compliant for GMP manufacturing

CS936X (COMMERCIAL SCALE)

• Designed and manufactured to customer specifications.
• Commercial scale peptide synthesizers having the largest installation base of any manufacturer.
• With reaction vessels ranging from 5L to 800L,
• We can meet the needs of any customer requirements for large scale peptide synthesis.
• Systems can be designed to meet ATEX, NEC, and additional regional hazardous environment standards.
• This includes the use of all explosion proof equipment for explosive gas atmospheres in the hazardous location, the include motors, sensors, thin clients, etc.
• Our systems can be designed to accommodate your factory depending on the use of a safe room for electrical components, or the use of a purged enclosure.
• Support with DQ, FAT, IQ/OQ.
• Fully validated software for process development or cGMP production.
• 21 CFR Part 11 Compliant for GMP manufacturing
• Available with both CSBio CSPEPM and Rockwell Automation Control system
• Also, guide users through lab setup and pass on industry tips and tricks learned from in house cGMP and R&D synthesis, which is invaluable for those entering the pilot space for the first time.